10        20        30        40        50        60        70        80        90       100       110       120                    
                           ....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|
Homo sapiens               -----------------MTKIKADPDGPEAQAEACSGERTYQELLVNQNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVMCEDRNL 
Pongo pygmaeus             -----------------MTKIKADPDGPEAQAEACSGERTYQELLVNQNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVMCEDRNL 
Mus musculus               -----------------MTKVKAAPEESEAQAEGCSEERTYKELLVNLNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVLCEDQNL 
Bos taurus                 -----------------MTKIKADPDGPEAQADACCGERTYHELLVNLNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFINKGEKGIMVLAGDTLPIEVYCHLPVMCEDRNL 
Xenopus tropicalis         -----------------MTKAKKEESE----EVPETPSKSYDELLAYLNPIAKPLAGRKLTKKLYKCVKKAIKQKNIRRGVKEVQKFINKGEKGIVVMAGDTLPIEVYCHIPVMCEDRGI 
Danio rerio                -----------------MTKVKKEKAG---EEETGGTEKSYQELIANINPIANPLASRKLSKKLYKCVKKAAKVKQIRRGVKEVQKFINKGETGIVVFAGDTLPIDVYCHLPIMCEDRSL 
Saccharomyces cerevisiae   MVNGSLGSRETETSAVKMGKDNKEHKESK----ESKTVDNYEARMPAVLPFAKPLASKKLNKKVLKTVKKASKAKNVKRGVKEVVKALRKGEKGLVVIAGDISPADVISHIPVLCEDHSV 
Schizosaccharomyces pombe  -----------------MAKDKKDHKHS------GSTEDEYDSYLPALMPIAKPLAPKKLNKKMMKTVKKASKQKHILRGVKEVVKAVRKGEKGLVILPGDISPMDVISHIPVLCEDNNV 

                                   130       140       150       160       170       180     
                           ....|....|....|....|....|....|....|....|....|....|....|....|.
Homo sapiens               PYVYIPSKTDLGAAAGSKRPTCVIMVKP-----------HEEYQEAYDECLEEVQSLPLPL 
Pongo pygmaeus             PYVYIPSKTDLGAAAGSKRPTCVIMVKP-----------HDEYQEAYDECLEEVQSLPLPL 
Mus musculus               PYVYIPSKTDLGAATGSKRPTCVIMVKP-----------HEEYQETYDKCLEEVQALPTPL 
Bos taurus                 PYVYIPSKTDLGAAAGSKRPTCVIMVKP-----------HEEYQEAYDECLEEVQALPPPM 
Xenopus tropicalis         PYSYVPSKSDLGAAAGSKRPTCVILIKP-----------HEDYQEAYDECLEDVQALPLPY 
Danio rerio                PYAYVPSKVDLGSSAGSKRPTCVIMIKP-----------HDEYKEAYDECVEEVTSLPKPI 
Saccharomyces cerevisiae   PYIFIPSKQDLGAAGATKRPTSVVFIVPGSNKKKDGKNKEEEYKESFNEVVKEVQAL---- 
Schizosaccharomyces pombe  PYLYTVSKELLGEASNTKRPTSCVMIVPGG-KKKD-MSKVEEYKESYEEIIKEVPALEV--